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Nature, J Clin Invest, Cell Rep, Nat Chem Biol, PNAS: our 5 latest publications


Genomic characterization of metastatic breast cancers.

Bertucci F, Ng CKY, Patsouris A, Droin N, Piscuoglio S, Carbuccia N, Soria JC, Tran Dien A, Adnani Y, Kamal M, Garnier S, Meurice G, Jimenez M, Tabernero J, Chia S, Martinalbo J, Perez-Moreno P, Dogan S, Verret B, Chaffanet M, Bacelot T, Campone M, Lefeuvre C, Bonnefoi H, Dalenc F, Jacquet A, De Filippo MR, Babbar N, Birnbaum D, Filleron D, Le Tourneau C & André F.

Nature 2019, doi.org/10.1038/s41586-019-1056-z

 

 

Ligand-based design of a potent inhibitor of NUPR1 exerting anticancer activity via necroptosis

Santofimia-Catano P, Xia Y, Lan W, Zhou Z, Huang C, Peng L, Soubeyran P, Velazquez-Campoy A, Abian O, Rizzuti B, Neira JL, Iovanna JL.

Journal of Clinical Investigations 2019, doi.org/10.1172/JCI127223

www.ncbi.nlm.nih.gov/pubmed/30920390

 

Nidogen-1 contributes to the interaction network involved in pro B cell retention in the perisinusoidal hematopoietic stem cell niche.

Balzano M, De Grandis M, Vu-Manh T-P, Chasson L, Bardin F, Farina A, Sergé A, Bidaut G, Charbord P, Herault, Bailly A-L, Michaud Cartier A, Boned A, Dalod M, Duprez E, Genever P, Coles M, Bajenoff M, Xerri L, Aurrand-Lions M, Schiff C & Mancini S

Cell Reports 2019 doi 10.1016/j.celrep.2019.02.065

doi.org/10.1016/j.celrep.2019.02.065

 

PH-domain-binding inhibitors of nucleotide exchange factor BRAG2 disrupt Arf GTPase signaling.

Nawrotek A, Benabdi S, Niyomchon S, Kryszke MH, Ginestier C, Cañeque T, Tepshi L, Mariani A, St Onge RP, Giaever G, Nislow C, Charafe-Jauffret E, Rodriguez R, Zeghouf M, Cherfils J.

Nat Chem Biol. 2019 Feb 11. doi: 10.1038/s41589-019-0228-3.

www.nature.com/articles/s41589-019-0228-3

 

TP53INP1 deficiency maintains murine B lymphopoiesis in aged bone marrow through redox-controlled IL-7R/STAT5 signaling

Zidi B, Vincent-Fabert C, Pouyet L, Seillier M, Vandevelde A, N’uessan P, Poplineau M, Guittard G, Mancini S, Duprez E & Carrier A

Proc Natl Acad Sci U S A. 2018 Dec 17. pii: 201809980. doi: 10.1073/pnas.1809980116.

www.pnas.org/content/early/2018/12/13/1809980116

 

 

 

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